Ancient proteins have been discovered and found to be capable of editing modern human cells.
Scientists have successfully created new CRISPR systems by injecting these ancient proteins into human cells.
New research suggests that some of the oldest Cas enzymes are able to cut DNA without PAMs (protective agents).
The ancient Cas proteins are not detected by the human immune system, making them ideal for therapeutic applications.
Francis Mojica, a biologist who studied microbes in the salt flats of Santa Pola, is a co-author of the study conducted on these ancient proteins.
These new CRISPR systems are like Swiss army knives, with the ability to cut both double and single-stranded DNA and RNA sequences.
Researchers are working on making these ancient Cas proteins as efficient as modern CRISPRs, or even better.
The discovery of these ancient proteins could help us understand the origin and evolution of CRISPR systems.
The primitive Cas proteins open up the possibility of designing completely new forms of synthetic CRISPR that don’t exist in nature.
Scientists are using the ancient Cas proteins to develop methods for correcting genetic defects in patients with ALS (Amyotrophic Lateral Sclerosis).
Researchers are exploring the potential of these ancient proteins in generating new biotechnologies.
The discoveries made by this research could lead to new medical treatments and therapies in the near future.
Miguel Ángel Moreno Mateos, an expert in gene-editing, has lauded the study as “particularly fascinating” and filled with considerable potential.
The ancient Cas proteins could also be used to create new gene-editing tools with more precision and accuracy.
This revolutionary technique has the potential to revolutionize genetic engineering and biotechnology development.